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June 2022: Pregnancy does not impact the effectiveness of chemotherapy for breast cancer.

30.06.2022

We are pleased to inform you that outcome of pregnant breast cancer patients treated with chemotherapy versus non-pregnant controls has been published in European Journal of Cancer

In this study survival of pregnant breast cancer patients treated with chemotherapy during pregnancy was compared to non-pregnant breast cancer patients treated with chemotherapy. Patients were diagnosed after 2000, excluding patients older than 45 years or with a postpartum diagnosis. The data was registered in two multicenter registries (the International Network of Cancer, Infertility and Pregnancy and the German Breast Group). In total, 662 pregnant and 2081 non-pregnant patients were selected.

Highlights:

  • Pregnant breast cancer patients have similar survival as non-pregnant controls.
  • Pregnancy does not impact the effectiveness of chemotherapy for breast cancer.
  • This cohort study supports initiation of chemotherapy for pregnant breast cancer when indicated.

Conclusion: Outcome of women with breast cancer treated with chemotherapy during pregnancy is comparable to young non-pregnant women. These results support chemotherapy for pregnant breast cancer when indicated.

Amant F, Nekljudova V, Maggen C, et al. Outcome of breast cancer patients treated with chemotherapy during pregnancy compared with non-pregnant controls. Eur J Cancer. 2022 Jul;170:54-63. doi: 10.1016/j.ejca.2022.04.014.


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